Bioelectricity: Electric model of the cell membrane
Computing the resting membrane potential and membrane properties
Use the GHK equation (at a temperature of \(29.2\;{}^{\circ}\mathrm{C}\) ) to calculate the membrane potential in mV for a cell model in which
- only the ions \(\mathrm{K}^{+}\) and \(\mathrm{Na}^{+}\) play a role;
- the concentration of \(\mathrm{K}^{+}\) inside the cell is \(158\;\mathrm{mM}\) and outside the cell is \(4.3\;\mathrm{mM}\);
- the concentration of \(\mathrm{Na}^{+}\) inside the cell is \(9.5\;\mathrm{mM}\) and outside the cell is \(143.0\;\mathrm{mM}\);
- the following ratio of permeabilities may be used \(P_\mathrm{K}\;:\;P_\mathrm{Na}=1\;:\;0.05\).
| \(V_m={}\) | mV (rounded to one decimal place) |
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