Gene regulation: Dynamical system for proteins
Gene expression in combination with protein degradation II
We again assume that the degradation can be modelled as exponential decay with characteristic time . We start with protein formation with an inhibiting transcription factor R. Then:
The differential equation for the concentration of the protein X is:
This again is a differential equation of limited exponential growth. We first determine the steady state solution by setting equal to zero:
The differential equation can be rewritten as
Then the time course of the concentration is
Note The above formulas for protein concentration correspond to Formulas 8-7A and 8-7C in Alberts et al. (2015, 6th ed., p. 515) when you use the following substitutions in the formulas of the book: .
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