Bioelectricity: Electric model of the cell membrane
Computing the resting membrane potential and membrane properties
Use the GHK equation (at a temperature of \(29.2\;{}^{\circ}\mathrm{C}\) ) to calculate the membrane potential in mV for a cell model in which
- only the ions \(\mathrm{Cl}^{-}\) and \(\mathrm{K}^{+}\) play a role;
- the concentration of \(\mathrm{Cl}^{-}\) inside the cell is \(5.5\;\mathrm{mM}\) and outside the cell is \(119\;\mathrm{mM}\);
- the concentration of \(\mathrm{K}^{+}\) inside the cell is \(139.0\;\mathrm{mM}\) and outside the cell is \(2.7\;\mathrm{mM}\);
- the following ratio of permeabilities may be used \(P_\mathrm{K}\;:\;P_\mathrm{Cl}=1\;:\;0.20\).
| \(V_m={}\) | mV (rounded to one decimal place) |
Unlock full access
