Bioelectricity: Electric model of the cell membrane
Computing the resting membrane potential and membrane properties
Use the GHK equation (at a temperature of \(29.2\;{}^{\circ}\mathrm{C}\) ) to calculate the membrane potential in mV for a cell model in which
- only the ions \(\mathrm{Na}^{+}\) and \(\mathrm{Cl}^{-}\) play a role;
- the concentration of \(\mathrm{Na}^{+}\) inside the cell is \(50.5\;\mathrm{mM}\) and outside the cell is \(460\;\mathrm{mM}\);
- the concentration of \(\mathrm{Cl}^{-}\) inside the cell is \(52.5\;\mathrm{mM}\) and outside the cell is \(555.0\;\mathrm{mM}\);
- the following ratio of permeabilities may be used \(P_\mathrm{Na}\;:\;P_\mathrm{Cl} = 0.03\;:\;0.25\).
| \(V_m={}\) | mV (rounded to one decimal place) |
Unlock full access
